Four-time Olympic Champion Mo Farah has separated with his coach and is moving back to Britain.
Farah, who won 5,000m and 10,000m gold at London 2012 and Rio 2016, said his decision was based on a desire to move back to London.
Salazar is being investigated by the US Anti-Doping Agency (Usada) after BBC’s Panorama made allegations about drugs use at his US training base.
“I’m moving back to London. I really miss home,” said Farah, 34.
He will now work with Gary Lough, who previously coached – and is married to – women’s marathon world record holder Paula Radcliffe.
Salazar said he has offered to continue working with Farah in an advisory role.
Farah has been coached by Cuba-born American Salazar at the Nike Oregon Project camp since 2011, winning six world titles in addition to his four Olympic golds.
Both Farah and Salazar deny they have ever broken anti-doping rules.
“I am a firm believer in clean sport and I strongly believe that anyone who breaks the rules should be punished,” Farah told the Sun.
“I’m not leaving the Nike Oregon Project and Alberto Salazar because of the doping allegations.
“This situation has been going on for over two years, if I was going to leave because of that I would have done.
“If Alberto had crossed the line I would be out the door, but Usada has not charged him with anything. If I had ever had any reason to doubt Alberto, I would not have stood by him all this time.”
Farah retired from track racing to concentrate on marathons after winning 10,000m gold and 5,000m silver at the World Championships in London in August.
He added: “I’m leaving simply because my family and I are moving back to London. We all loved spending our summer here and [Farah’s wife] Tania and I realised how much we have missed spending time with our friends and family – and the kids are so happy here, too.
“We want the kids to grow up in the UK. It’s the right thing to do for my family. But both Nike Oregon Project and Alberto are based in the USA, so it just would not be possible to continue our relationship from London.”
Farah said new coach Lough “has an in-depth understanding of what is needed to achieve real results at marathon distance”.