The big boys have arrived in the Carabao Cup, with the Premier League sides involved in European competition this year entering in the third round.
But the bigger they are, the harder they fall and the potential for giant killings has increased.
Leicester vs Liverpool
Leicester host Liverpool live on Sky Sports Football as the third round of the Carabao Cup gets underway on Tuesday.
Both sides will be looking to return to winning ways, with Leicester having lost two and drawn one of their last three matches and Liverpool with two draws and a defeat from their last three.
Danny Ings could feature for Liverpool as he continues his comeback from a second long-term knee injury.
Manchester United v Burton Albion
Following Paul Pogba’s injury last Tuesday in the Champions League, Jose Mourinho is likely to give a runout to his second-string players, hoping to avoid a similar occurrence.
Their Championship opponents have come along way since these sides last met in 2006, when Burton were in the Conference. Last round the visitors brought 33 fans to Cardiff – expect many more on Wednesday night.
The away team have beaten their opponents once in their history, yet that was in 1902 when the North London club was known as Woolwich Arsenal.
Tottenham Hotspur v Barnsley
Barnsley have been victorious on their last two trips to Wembley – winning the League One play-off Final and Football League Trophy in 2016.
Tottenham, meanwhile, are well aware of the ‘apparent curse’ the ground has on the players; they are yet to win there in the league this season.
Barnsley have struggles of their own, currently laying 20th in the Championship.
Crystal Palace v Huddersfield
One reason to be cheerful for Palace fans will be the return of Mahmadou Sakho, the defender who cost the club £26m.
After a woeful start to the season, the Frenchman should bolster Roy Hodgson’s defence as they face David Wagner’s gegenpressing Huddersfield side, who beat them 3-0 just over a month ago.
Chelsea v Nottingham Forest
This match-up has some prestige: it is the only third-round tie where both sides have won a European Cup.
Both also won the Full Members’ Cup a record two times; a trophy spawned from English teams’ ban from European competition.
Chelsea have weathered the storm since their opening day defeat (winning three and drawing one), while Nottingham Forest.